Diuretics and Masking Agents

What are Diuretics and Masking Agents?

Diuretics and Masking Agents are products that dilute or mask a urine sample used in drug testing or impair the excretion of a performance enhancing substance to conceal its presence in a urine sample. Masking Agents eliminate fluid from the body to hide or “mask” a performance enhancing substance. Diuretics reduce the concentration of a performance enhancing substance in the urine so the chance of detecting the performance enhancing substance is decreased.

Examples of Masking Agents include but are not limited to: Alpha-Reductase Inhibitors (i.e., Finasteride and Dutasteride), Epitestosterone, Probenecid and Plasma Expanders (i.e., Albumin, Dextran and Hydroxyethyl Starch).

Examples of Diuretics include but are not limited to: Acetazolamide, Amiloride, Bumetanide, Canrenone, Chlorthalidone, Ethacryrnic Acid, Furosemide, Indapamide, Metolazone, Spironolactone, Thiazides (i.e., Bendroflumethiazide, Chlorothiazide, Hydrochlorothiazide) and Triamterene.

What do Diuretics and Masking Agents look like?

Diuretics and Masking Agents can be in liquid or pill form.

How are Diuretics and Masking Agents used?

Diuretics and Masking Agents are typically administered with a performance enhancing substance to dilute and or mask a urine sample or to conceal the performance enhancing substance in the urine sample.

What are the short and long-term effects on the body?

The side effects associated with the use of Masking Agents include headache, nausea, dizziness, hot flushes (fever and chills), kidney stones, allergic reactions (skin rash and hives), anaphylactic shock, kidney stones, acute gouty arthritis, and hair loss.

The side effects associated with the use of Diuretics include heart arrhythmias, dehydration, muscle cramping, blood volume depletion, dizziness, significant drops in blood pressure, and severe electrolyte imbalances.

What is their federal classification?

To be used legally, these substances require a legitimate prescription from a physician.